Hibernating mammals rely on particular genes to adjust their metabolisms as they enter that unique, low-energy state — and humans actually carry that same hibernation-related DNA. Now, early research hints that leveraging this particular DNA could help treat medical conditions in people, scientists say. Hibernation offers “a whole bunch of different biometrically important superpowers,” senior … Read more
DNA that humans acquired from ancient viruses plays a key role in switching parts of our genetic code on and off, a new study has found. Nearly half of the human genome consists of segments called transposable elements (TEs), also known as “jumping genes” because they can hop around the genome. Some of these TEs … Read more
Up to 3 in every 1,000 newborns has hearing loss in one or both ears. While cochlear implants offer remarkable hope for these children, it requires invasive surgery. These implants also cannot fully replicate the nuance of natural hearing. But recent research my colleagues and I conducted has shown that a form of gene therapy … Read more
Disease name: Werner syndrome, sometimes called “adult progeria” Affected populations: Werner syndrome is estimated to affect 1 in 100,000 live births worldwide, though its prevalence varies among countries. In Japan, the syndrome affects an estimated 1 in 40,000 to 1 in 20,000 people, whereas the prevalence in the United States is around 1 in 200,000. … Read more
Some lucky people have rare genetic mutations that enable them to feel well-rested after just four hours of sleep, while the rest of us need around eight hours to function. Now, researchers have identified one of these mutations, named SIK3-N783Y, in a human super-sleeper. The team then studied the mutation in genetically modified mice and … Read more
Some people get the chills or feel moved to tears when listening to certain songs, while others tend to experience a less-intense reaction to music. Now, a new study hints that your level of music enjoyment may be partially written in your genes. According to a study published March 25 in the journal Nature Communications, … Read more
Dormant genes on the X chromosome may reawaken in old age, potentially giving the aging female brain a boost that the male brain doesn’t receive. This phenomenon may help to explain why, on many measures, females show a higher level of cognitive resilience in old age than males do. The findings come from a new … Read more
By disrupting a key gene, scientists made chicken feathers more dinosaur-like — but the results didn’t last. In a new study, researchers inhibited a gene during embryonic development to make chicken feathers more primitive, like the kind of simple tube-shaped proto-feathers that likely first emerged in the ancestors of dinosaurs in the Early Triassic 250 … Read more
Approximately 25 million years ago, an ancestor of both humans and apes genetically diverged from monkeys and lost its tail. No one had identified the genetic mutation responsible for this dramatic change in our physiology — until now. In a new study published Wednesday (Feb. 28) in the journal Nature, researchers identified a unique DNA … Read more
Several children born with a rare, inherited form of deafness can now hear thanks to two new gene therapies, clinical trial results show. Both therapies target the gene for otoferlin, a protein in the inner ear that lets nerve cells translate vibrations from sound into electrical signals that can be interpreted by the brain. Mutations … Read more
