Up to 3 in every 1,000 newborns has hearing loss in one or both ears. While cochlear implants offer remarkable hope for these children, it requires invasive surgery. These implants also cannot fully replicate the nuance of natural hearing. But recent research my colleagues and I conducted has shown that a form of gene therapy … Read more
By disrupting a key gene, scientists made chicken feathers more dinosaur-like — but the results didn’t last. In a new study, researchers inhibited a gene during embryonic development to make chicken feathers more primitive, like the kind of simple tube-shaped proto-feathers that likely first emerged in the ancestors of dinosaurs in the Early Triassic 250 … Read more
Cancer can sometimes thwart drugs designed to treat it — but now, scientists have developed a way to turn tumor cells against their neighbors, forcing the cancer to cooperate with treatment. A cancer treatment’s success hinges on its capacity to damage cancer cells enough to kill them or stop them from growing. However, some cancer … Read more
Approximately 25 million years ago, an ancestor of both humans and apes genetically diverged from monkeys and lost its tail. No one had identified the genetic mutation responsible for this dramatic change in our physiology — until now. In a new study published Wednesday (Feb. 28) in the journal Nature, researchers identified a unique DNA … Read more
Several children born with a rare, inherited form of deafness can now hear thanks to two new gene therapies, clinical trial results show. Both therapies target the gene for otoferlin, a protein in the inner ear that lets nerve cells translate vibrations from sound into electrical signals that can be interpreted by the brain. Mutations … Read more
Why do common shrews live for only two years, while bowhead whales survive for two centuries? And could the answer give us hints as to how to extend our own, human life spans? The maximum life span of each species is estimated using the age of its longest-living member, and these vary by orders of … Read more
Neanderthal genes may be one cause of the disorder nicknamed the “Viking disease,” in which fingers become frozen in a bent position, a new study finds. The study, published June 14 in the journal Molecular Biology and Evolution, finds gene variants that were inherited from Neanderthals that dramatically increase the odds of developing the condition, … Read more
Two children who experienced intense, insatiable hunger that drove them to overeat have rare, never-before-seen genetic mutations that interfere with leptin, a key hormone that helps tell the body when it is full, a new case report says. After white fat cells make leptin, it plugs into the brainstem and hypothalamus, brain regions that help … Read more
Scientists have long debated the greatest possible age of a person, with previous studies placing the limit at up to 150 years. But in the past 25 years, no one has surpassed the record for the world’s oldest person, held by Jean Louise Calment, who died at age 122 in 1997. “This has led people … Read more
Telomeres are the “caps” that protect the ends of DNA strands from being destroyed by a cell. They are made up of areas of repeated DNA sequences combined with specific proteins at the ends of chromosomes — the tightly wound structures of DNA and proteins inside cells. Telomeres play a role in how fast cells … Read more
